PMF1-BGLAP

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PMF1-BGLAP mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PMF1-BGLAP-associated genes across cancer lineages are MIR4752. Each is linked with PMF1-BGLAP in more than 1 cancer types. Because this analysis shows association rather than direction, both PMF1-BGLAP-to-partner and partner-to-PMF1-BGLAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4752 grouped by PMF1-BGLAP-low versus PMF1-BGLAP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PMF1-BGLAP→partner) and Y-score (partner→PMF1-BGLAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR4752 →+0.618+8.066<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

MIR4752 by PMF1-BGLAP expression — UCEC

Box plot of MIR4752 in PMF1-BGLAP-low vs PMF1-BGLAP-high samples in UCEC.

Explore this box plot interactively →

Exploration