PMAIP1

Across TCGA patient cohorts, PMAIP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,003 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PMAIP1-associated proteins across cancer lineages are PPP1R18_S224, NCF2, and NCF4. Each is linked with PMAIP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PMAIP1-to-partner and partner-to-PMAIP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PMAIP1 versus PPP1R18_S224 in OV, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PMAIP1→partner) and Y-score (partner→PMAIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PPP1R18_S224 →	+0.799	+0.993	.004	.006	3	6
GBM	NCF2 →	+0.765	+1.211	<.001	<.001	3	5
COAD	NCF4 →	+0.513	+1.103	<.001	<.001	3	5
GBM	P3H1 →	+0.724	+1.151	<.001	<.001	3	5
HNSC	PRKAR2A →	-0.295	-0.915	<.001	<.001	3	5
PDAC	CRTAP →	+0.562	+0.969	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,003 associations by consensus.

PMAIP1 vs PPP1R18_S224 — OV

Explore this scatter interactively →