PMAIP1

Across TCGA patient cohorts, PMAIP1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,908 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PMAIP1-associated genes across cancer lineages are AK6, ARMC12, and H2BC7. Each is linked with PMAIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PMAIP1-to-partner and partner-to-PMAIP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PMAIP1 versus AK6 in LUAD, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PMAIP1→partner) and Y-score (partner→PMAIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	AK6 →	+0.407	+2.520	.001	.009	3	2
BRCA	ARMC12 →	-1.336	-2.098	.001	.001	3	2
BRCA	H2BC7 →	-2.395	-1.910	.001	.002	3	2
LUAD	HSPA9 →	+0.786	+2.519	.003	.009	3	1
LUAD	USP6 →	-0.290	-2.519	.006	.009	3	1
LUAD	CYP17A1 →	-0.168	-2.520	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,908 associations by consensus.

PMAIP1 vs AK6 — LUAD

Explore this scatter interactively →