PMAIP1

Across TCGA cell cohorts, PMAIP1 RNA expression is significantly associated with the RNA expression of many other genes, with 10,584 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PMAIP1-associated genes across cancer lineages are IFIT3, CD274, and TRIM8. Each is linked with PMAIP1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PMAIP1-to-partner and partner-to-PMAIP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PMAIP1 versus IFIT3 in SOFT_TISSUE, with a Pearson correlation of 0.42.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PMAIP1→partner) and Y-score (partner→PMAIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	IFIT3 →	+2.578	+2.046	.001	.004	3	10
STOMACH	CD274 →	+2.562	+2.221	<.001	<.001	3	9
PANCREAS	TRIM8 →	+1.129	+1.856	.001	<.001	3	8
LIVER	PDP1 →	+2.774	+3.935	.001	<.001	2	9
SKIN	ARNTL2 →	+1.872	+1.301	<.001	<.001	3	8
BREAST	IRF1 →	+1.759	+1.997	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,584 associations by consensus.

PMAIP1 vs IFIT3 — SOFT_TISSUE

Explore this scatter interactively →