PLXNB1

Across TCGA patient cohorts, PLXNB1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,065 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLXNB1-associated genes across cancer lineages are TCF19, APOBEC3G, and SH2D2A. Each is linked with PLXNB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PLXNB1-to-partner and partner-to-PLXNB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLXNB1 versus TCF19 in GBM, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLXNB1→partner) and Y-score (partner→PLXNB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TCF19 →	-0.795	-0.373	<.001	.002	3	5
OV	APOBEC3G →	-1.021	-0.306	.001	.007	3	4
BRCA	SH2D2A →	-0.934	-0.284	.001	.002	3	4
LUAD	CENPL →	-0.544	-0.197	.001	.005	3	4
CCRCC	RUFY4 →	-0.608	-0.242	<.001	.001	3	4
UCEC	GIMAP2 →	-0.734	-0.220	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,065 associations by consensus.

PLXNB1 vs TCF19 — GBM

Explore this scatter interactively →