PLXNB1

Across TCGA cell cohorts, PLXNB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,448 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PLXNB1-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Post-transcriptional gene silencing, and Protein localization to cytoplasmic stress granule. Each is linked with PLXNB1 in more than 14 cancer types. Because this analysis shows association rather than direction, both PLXNB1-to-partner and partner-to-PLXNB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by PLXNB1-low versus PLXNB1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLXNB1→partner) and Y-score (partner→PLXNB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.112	+2.320	<.001	<.001	3	15
BONE	Post-transcriptional gene silencing →	+0.097	+1.422	<.001	.004	3	15
BONE	Protein localization to cytoplasmic stress granule →	+0.161	+1.589	<.001	.001	3	15
OVARY	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.101	+1.979	<.001	<.001	3	15
SOFT_TISSUE	Negative regulation of mRNA catabolic process →	+0.079	+1.137	<.001	<.001	3	15
KIDNEY	Cilium or flagellum-dependent cell motility →	-0.093	-1.826	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,448 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by PLXNB1 expression — OVARY

Explore this box plot interactively →