PLXNA1

Across TCGA cell cohorts, PLXNA1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,346 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PLXNA1-associated genes across cancer lineages are AK3, GMEB1, and SAMD13. Each is linked with PLXNA1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PLXNA1-to-partner and partner-to-PLXNA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLXNA1 versus AK3 in STOMACH, with a Pearson correlation of -0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLXNA1→partner) and Y-score (partner→PLXNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	AK3 →	-1.249	-1.126	.001	.009	3	4
CNS	GMEB1 →	+0.487	+0.735	.004	.005	3	4
BLOOD_Leukemia	SAMD13 →	-0.833	-0.634	.005	.002	3	4
BREAST	ZC3H8 →	-1.037	-1.379	.008	<.001	3	3
BREAST	A1CF →	-0.037	-1.068	.003	.002	3	3
BREAST	MRPL57 →	+0.631	+0.841	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,346 associations by consensus.

PLXNA1 vs AK3 — STOMACH

Explore this scatter interactively →