PLIN4

Across TCGA cell cohorts, PLIN4 mutation is significantly associated with the RNA expression of many other genes, with 365 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PLIN4-associated genes across cancer lineages are PPIAL4F, TFDP3, and C6orf118. Each is linked with PLIN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLIN4-to-partner and partner-to-PLIN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPIAL4F grouped by PLIN4-low versus PLIN4-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLIN4→partner) and Y-score (partner→PLIN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	PPIAL4F →	+0.073	+4.930	<.001	.008	3	2
BLOOD_Leukemia	TFDP3 →	+0.007	+3.684	<.001	.004	3	2
LARGE_INTESTINE	C6orf118 →	+0.061	+1.793	.008	.004	3	2
LARGE_INTESTINE	SELENOK →	+0.434	+2.850	.008	<.001	3	2
LARGE_INTESTINE	CTSS →	-2.377	-3.863	<.001	<.001	3	2
LARGE_INTESTINE	RCHY1 →	+0.780	+3.652	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 365 associations by consensus.

PPIAL4F by PLIN4 expression — SOFT_TISSUE

Explore this box plot interactively →