PLGLB2

Across TCGA patient cohorts, PLGLB2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,944 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PLGLB2-associated genes across cancer lineages are LPCAT2, RAB38, and KSR1. Each is linked with PLGLB2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PLGLB2-to-partner and partner-to-PLGLB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLGLB2 versus LPCAT2 in UCEC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLGLB2→partner) and Y-score (partner→PLGLB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LPCAT2 →	+0.641	+0.354	.007	.008	3	3
LUAD	RAB38 →	+1.232	+0.571	<.001	<.001	3	3
LUAD	KSR1 →	-1.007	-0.597	<.001	<.001	3	3
HNSC	PDE3B →	-0.741	-0.498	.001	.001	3	3
HNSC	IVL →	+2.318	+0.658	<.001	<.001	3	3
HNSC	RHOD →	+0.859	+0.407	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,944 associations by consensus.

PLGLB2 vs LPCAT2 — UCEC

Explore this scatter interactively →