Across TCGA patient cohorts, PLET1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,042 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PLET1-associated proteins across cancer lineages are CAVIN1, LMNA, and SEPTIN4. Each is linked with PLET1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PLET1-to-partner and partner-to-PLET1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLET1→partner) and Y-score (partner→PLET1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CAVIN1 →	+0.675	+0.388	<.001	<.001	3	4
UCEC	LMNA →	+0.694	+0.716	<.001	<.001	3	4
UCEC	SEPTIN4 →	+0.454	+0.483	<.001	.002	3	4
UCEC	AGO3 →	+0.392	+0.554	<.001	.001	3	4
PDAC	LMNB2 →	+0.393	+0.421	<.001	<.001	3	4
CCRCC	PLAC9 →	+0.610	+0.329	.006	.008	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,042 associations by consensus.

Exploration

PLET1 survival (RNA) · tumor vs normal (RNA) · all PLET1 data types