Across TCGA patient cohorts, PLET1 mutation is significantly associated with the RNA expression of many other genes, with 80 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLET1-associated genes across cancer lineages are CFC1, LINC02667, and SLIT1-AS1. Each is linked with PLET1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLET1-to-partner and partner-to-PLET1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLET1→partner) and Y-score (partner→PLET1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	CFC1 →	+0.027	+5.418	<.001	.005	3	1
CESC	LINC02667 →	+0.187	+5.010	<.001	.009	3	1
CESC	SLIT1-AS1 →	+0.065	+5.418	<.001	.005	3	1
CESC	RPL32P30 →	+0.257	+5.010	<.001	.009	3	1
CESC	LINC01487 →	+0.051	+5.010	<.001	.009	3	1
UCEC	RUNDC1 →	+0.547	+3.330	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 80 associations by consensus.

Exploration

PLET1 survival (RNA) · tumor vs normal (RNA) · all PLET1 data types