PLEKHG4B

Across TCGA patient cohorts, PLEKHG4B RNA expression is significantly associated with the RNA expression of many other genes, with 16,053 significant associations in total. UVM shows the largest number of these associations.

The most reproducible PLEKHG4B-associated genes across cancer lineages are ZNF618, STARD4-AS1, and GABBR1. Each is linked with PLEKHG4B in more than 26 cancer types. Because this analysis shows association rather than direction, both PLEKHG4B-to-partner and partner-to-PLEKHG4B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLEKHG4B versus ZNF618 in CHOL, with a Pearson correlation of 0.64.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLEKHG4B→partner) and Y-score (partner→PLEKHG4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CHOL	ZNF618 →	+1.352	+2.612	<.001	<.001	2	27
MESO	STARD4-AS1 →	+0.943	+1.017	<.001	.001	3	26
LAML	GABBR1 →	+1.680	+0.570	<.001	.001	3	24
SARC	MEX3A →	+1.448	+1.079	<.001	<.001	3	24
OV	ZNF496 →	+0.788	+1.254	<.001	<.001	3	24
SCLC	DNMT3A →	+1.950	+1.183	.001	<.001	2	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,053 associations by consensus.

PLEKHG4B vs ZNF618 — CHOL

Explore this scatter interactively →