PLEKHG4B

Across TCGA cell cohorts, PLEKHG4B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,041 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PLEKHG4B-associated GO terms across cancer lineages are mRNA export from nucleus, mRNA transport, and Establishment of RNA localization. Each is linked with PLEKHG4B in more than 13 cancer types. Because this analysis shows association rather than direction, both PLEKHG4B-to-partner and partner-to-PLEKHG4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA export from nucleus grouped by PLEKHG4B-low versus PLEKHG4B-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLEKHG4B→partner) and Y-score (partner→PLEKHG4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	mRNA export from nucleus →	+0.146	+2.210	.002	<.001	3	13
OESOPHAGUS	mRNA transport →	+0.154	+2.143	.002	<.001	3	13
OESOPHAGUS	Establishment of RNA localization →	+0.091	+1.809	<.001	<.001	3	13
LUNG_SCLC	Regulation of cell cycle G1/S phase transition →	+0.059	+1.868	.003	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of G1/S transition of mitotic cell cycle →	+0.049	+1.619	.006	<.001	2	14
OESOPHAGUS	Nucleic acid transport →	+0.091	+1.809	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,041 associations by consensus.

mRNA export from nucleus by PLEKHG4B expression — OESOPHAGUS

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