PLEKHA8P1

Across TCGA patient cohorts, PLEKHA8P1 protein abundance is significantly associated with the RNA expression of many other genes, with 93 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLEKHA8P1-associated genes across cancer lineages are FNDC3A, NEDD9, and MRPL18. Each is linked with PLEKHA8P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLEKHA8P1-to-partner and partner-to-PLEKHA8P1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLEKHA8P1 versus FNDC3A in GBM, with a Pearson correlation of -0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLEKHA8P1→partner) and Y-score (partner→PLEKHA8P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FNDC3A →	-0.860	-0.672	.005	.007	3	1
GBM	NEDD9 →	-0.996	-0.672	.006	.007	3	1
GBM	MRPL18 →	-0.264	-0.672	.005	.007	3	1
GBM	TMEM131L →	-0.618	-0.672	<.001	.007	3	1
GBM	ZC3H13 →	-0.648	-0.672	.002	.007	3	1
GBM	NPHP4 →	+1.733	+1.089	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 93 associations by consensus.

PLEKHA8P1 vs FNDC3A — GBM

Explore this scatter interactively →