PLCE1

Across TCGA cell cohorts, PLCE1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,021 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PLCE1-associated genes across cancer lineages are GCN1, RPLP0, and POP5. Each is linked with PLCE1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PLCE1-to-partner and partner-to-PLCE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLCE1 versus GCN1 in LIVER, with a Pearson correlation of 0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLCE1→partner) and Y-score (partner→PLCE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	GCN1 →	+1.180	+1.302	.004	.004	3	10
CNS	RPLP0 →	+1.068	+1.103	<.001	<.001	3	8
STOMACH	POP5 →	+0.839	+1.183	.004	.002	3	7
STOMACH	PA2G4 →	+1.036	+1.193	.001	.008	3	7
LIVER	PGAM5 →	+1.225	+1.078	.007	.001	3	7
PANCREAS	FARSA →	+1.014	+1.398	.003	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,021 associations by consensus.

PLCE1 vs GCN1 — LIVER

Explore this scatter interactively →