PLAU

Across TCGA patient cohorts, PLAU protein abundance is significantly associated with the protein abundance of many other proteins, with 25,438 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLAU-associated proteins across cancer lineages are UPP1, C1R, and FN1. Each is linked with PLAU in more than 9 cancer types. Because this analysis shows association rather than direction, both PLAU-to-partner and partner-to-PLAU results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLAU versus UPP1 in OV, with a Pearson correlation of 0.41.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLAU→partner) and Y-score (partner→PLAU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	UPP1 →	+0.605	+0.742	<.001	<.001	3	10
CCRCC	C1R →	+0.803	+0.888	<.001	.001	3	10
OV	FN1 →	+1.212	+1.034	<.001	<.001	3	10
OV	SULF1 →	+1.090	+0.874	<.001	<.001	3	9
OV	PLAUR →	+0.766	+1.094	<.001	<.001	3	9
GBM	PLOD1 →	+0.742	+0.823	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,438 associations by consensus.

PLAU vs UPP1 — OV

Explore this scatter interactively →