PLAAT4

Across TCGA cell cohorts, PLAAT4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,912 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PLAAT4-associated GO terms across cancer lineages are CD8-positive, alpha-beta T cell activation, Negative regulation of viral process, and Phosphatidylethanolamine acyl-chain remodeling. Each is linked with PLAAT4 in more than 16 cancer types. Because this analysis shows association rather than direction, both PLAAT4-to-partner and partner-to-PLAAT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8-positive, alpha-beta T cell activation grouped by PLAAT4-low versus PLAAT4-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLAAT4→partner) and Y-score (partner→PLAAT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	CD8-positive, alpha-beta T cell activation →	+0.180	+3.556	<.001	<.001	3	17
BONE	Negative regulation of viral process →	+0.134	+3.285	<.001	<.001	3	17
LARGE_INTESTINE	Phosphatidylethanolamine acyl-chain remodeling →	+0.135	+2.847	<.001	<.001	3	16
LIVER	Cytolysis in another organism →	+2.021	+3.721	<.001	<.001	3	16
SOFT_TISSUE	CD8-positive, alpha-beta T cell differentiation →	+0.116	+2.085	<.001	.006	3	16
SOFT_TISSUE	N-acylphosphatidylethanolamine metabolic process →	+0.502	+2.150	.003	.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,912 associations by consensus.

CD8-positive, alpha-beta T cell activation by PLAAT4 expression — BREAST

Explore this box plot interactively →