PLA2G4A

Across TCGA patient cohorts, PLA2G4A protein abundance is significantly associated with the RNA expression of many other genes, with 14,772 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PLA2G4A-associated genes across cancer lineages are PACERR, PTGS2, and FAM89A. Each is linked with PLA2G4A in more than 7 cancer types. Because this analysis shows association rather than direction, both PLA2G4A-to-partner and partner-to-PLA2G4A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLA2G4A versus PACERR in LUAD, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G4A→partner) and Y-score (partner→PLA2G4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PACERR →	+1.216	+1.026	<.001	<.001	3	8
LUAD	PTGS2 →	+1.988	+1.107	<.001	<.001	3	7
BRCA	FAM89A →	+1.006	+0.471	<.001	<.001	3	5
GBM	CARD6 →	+0.846	+0.681	<.001	<.001	3	5
GBM	TNFRSF11A →	+0.842	+0.625	<.001	<.001	3	5
LSCC	CXCL3 →	+1.105	+0.504	<.001	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,772 associations by consensus.

PLA2G4A vs PACERR — LUAD

Explore this scatter interactively →