PLA2G4A

Across TCGA cell cohorts, PLA2G4A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,152 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PLA2G4A-associated GO terms across cancer lineages are Positive regulation of platelet activation, Olefinic compound metabolic process, and Nicotinamide nucleotide metabolic process. Each is linked with PLA2G4A in more than 13 cancer types. Because this analysis shows association rather than direction, both PLA2G4A-to-partner and partner-to-PLA2G4A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of platelet activation grouped by PLA2G4A-low versus PLA2G4A-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLA2G4A→partner) and Y-score (partner→PLA2G4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of platelet activation →	-0.357	-2.001	<.001	<.001	3	14
BONE	Olefinic compound metabolic process →	+0.081	+1.633	.003	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Nicotinamide nucleotide metabolic process →	+0.078	+1.510	.001	.002	3	8
SOFT_TISSUE	Positive regulation of fever generation →	+0.713	+1.239	<.001	<.001	3	8
OESOPHAGUS	Icosanoid secretion →	+0.091	+1.706	.001	<.001	3	8
URINARY_TRACT	Negative regulation of delayed rectifier potassium channel activity →	+1.318	+1.808	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,152 associations by consensus.

Positive regulation of platelet activation by PLA2G4A expression — LIVER

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