PKNOX2-AS1

Across TCGA patient cohorts, PKNOX2-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,976 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PKNOX2-AS1-associated GO terms across cancer lineages are Roof of mouth development, Ventricular septum morphogenesis, and Mesenchymal cell differentiation. Each is linked with PKNOX2-AS1 in more than 17 cancer types. Because this analysis shows association rather than direction, both PKNOX2-AS1-to-partner and partner-to-PKNOX2-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Roof of mouth development grouped by PKNOX2-AS1-low versus PKNOX2-AS1-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PKNOX2-AS1→partner) and Y-score (partner→PKNOX2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Roof of mouth development →	+0.061	+0.297	<.001	<.001	3	18
TGCT	Ventricular septum morphogenesis →	+0.072	+0.350	<.001	<.001	3	18
TGCT	Mesenchymal cell differentiation →	+0.066	+0.322	<.001	<.001	3	17
STAD	Regulation of small GTPase mediated signal transduction →	+0.053	+0.054	<.001	<.001	3	17
STAD	Hematopoietic stem cell homeostasis →	+0.063	+0.057	<.001	<.001	3	17
STAD	Negative regulation of autophagy →	+0.060	+0.058	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,976 associations by consensus.

Roof of mouth development by PKNOX2-AS1 expression — TGCT

Explore this box plot interactively →