PKN3

Across TCGA patient cohorts, PKN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,362 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PKN3-associated proteins across cancer lineages are SUPT16H, EHMT1, and GTF3C4. Each is linked with PKN3 in more than 6 cancer types. Because this analysis shows association rather than direction, both PKN3-to-partner and partner-to-PKN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PKN3 versus SUPT16H in GBM, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PKN3→partner) and Y-score (partner→PKN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SUPT16H →	+0.445	+0.587	<.001	<.001	3	7
GBM	EHMT1 →	+0.332	+0.618	<.001	<.001	3	7
LSCC	GTF3C4 →	+0.420	+0.747	<.001	<.001	3	7
OV	MCM6 →	+0.716	+0.864	<.001	.001	3	7
GBM	NCAPH →	+0.562	+0.584	<.001	<.001	3	7
GBM	UHRF1 →	+0.599	+0.594	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,362 associations by consensus.

PKN3 vs SUPT16H — GBM

Explore this scatter interactively →