PKIA-AS1

Across TCGA patient cohorts, PKIA-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,297 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PKIA-AS1-associated proteins across cancer lineages are ZC2HC1A, PKIA, and ZC2HC1A_S223. Each is linked with PKIA-AS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PKIA-AS1-to-partner and partner-to-PKIA-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PKIA-AS1 versus ZC2HC1A in HNSC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PKIA-AS1→partner) and Y-score (partner→PKIA-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZC2HC1A →	+0.447	+0.712	<.001	<.001	3	5
PDAC	PKIA →	+0.951	+0.649	<.001	<.001	3	5
GBM	ZC2HC1A_S223 →	+0.833	+0.453	<.001	<.001	3	5
BRCA	HSPB1_S199 →	-0.565	-0.060	.006	.005	3	4
HNSC	PHF21A →	+0.235	+0.618	.004	.004	3	3
UCEC	PHKA1 →	-0.352	-0.392	<.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,297 associations by consensus.

PKIA-AS1 vs ZC2HC1A — HNSC

Explore this scatter interactively →