Across TCGA patient cohorts, PIWIL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,934 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PIWIL3-associated GO terms across cancer lineages are Negative regulation of mitotic cell cycle, Positive regulation of cell cycle process, and Positive regulation of mitotic cell cycle. Each is linked with PIWIL3 in more than 17 cancer types. Because this analysis shows association rather than direction, both PIWIL3-to-partner and partner-to-PIWIL3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIWIL3→partner) and Y-score (partner→PIWIL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of mitotic cell cycle →	+0.063	+0.243	<.001	<.001	3	18
THYM	Positive regulation of cell cycle process →	+0.060	+0.265	<.001	<.001	3	16
ESCA	Positive regulation of mitotic cell cycle →	+0.064	+0.219	<.001	.001	3	16
THYM	Mitotic cell cycle checkpoint signaling →	+0.075	+0.304	<.001	<.001	3	16
STAD	Mitochondrial membrane organization →	+0.068	+0.236	<.001	<.001	3	16
STAD	Positive regulation of cell cycle phase transition →	+0.058	+0.247	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,934 associations by consensus.

Exploration

PIWIL3 survival (RNA) · tumor vs normal (RNA) · all PIWIL3 data types