Across TCGA patient cohorts, PIWIL3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,102 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIWIL3-associated genes across cancer lineages are PIK3CG, HAUS8, and PRPSAP1. Each is linked with PIWIL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PIWIL3-to-partner and partner-to-PIWIL3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIWIL3→partner) and Y-score (partner→PIWIL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PIK3CG →	+0.976	+0.474	<.001	.002	3	2
GBM	HAUS8 →	-0.599	-0.543	.001	.001	3	2
LSCC	PRPSAP1 →	-0.408	-0.964	.001	<.001	3	2
LSCC	TNFSF13 →	+0.672	+0.895	.002	.002	3	2
LSCC	THOP1 →	-0.403	-0.826	.009	.002	3	2
LSCC	KLHL11 →	-0.461	-0.982	.004	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,102 associations by consensus.

Exploration

PIWIL3 survival (RNA) · tumor vs normal (RNA) · all PIWIL3 data types