PINLYP

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PINLYP RNA expression is significantly associated with the protein abundance of many other proteins, with 13,292 significant associations in total. COAD shows the largest number of these associations.

The most reproducible PINLYP-associated proteins across cancer lineages are TACO1, DNM1, and GRPEL1. Each is linked with PINLYP in more than 4 cancer types. Because this analysis shows association rather than direction, both PINLYP-to-partner and partner-to-PINLYP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PINLYP versus TACO1 in BRCA, with a Pearson correlation of -0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PINLYP→partner) and Y-score (partner→PINLYP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCATACO1 →-0.326-0.485.001<.00135
UCECDNM1 →+0.502+0.416<.001<.00135
UCECGRPEL1 →-0.447-0.461<.001<.00135
COADTPM4 →+0.508+0.350<.001<.00135
BRCATBCEL →+0.334+0.403<.001.00334
COADTBRG4 →-0.408-0.284<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,292 associations by consensus.

PINLYP vs TACO1 — BRCA

Per-sample scatter of PINLYP vs TACO1 in BRCA (Pearson r = -0.31).

Explore this scatter interactively →

Exploration