PINLYP

Across TCGA cell cohorts, PINLYP RNA expression is significantly associated with the go_rna of many other GO terms, with 1,832 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible PINLYP-associated GO terms across cancer lineages are Positive regulation of intracellular transport, Organic acid transport, and Leukocyte tethering or rolling. Each is linked with PINLYP in more than 6 cancer types. Because this analysis shows association rather than direction, both PINLYP-to-partner and partner-to-PINLYP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular transport grouped by PINLYP-low versus PINLYP-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PINLYP→partner) and Y-score (partner→PINLYP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Positive regulation of intracellular transport →	+0.032	+0.377	.002	.008	3	7
SKIN	Organic acid transport →	-0.041	-0.719	.001	.006	3	6
BREAST	Leukocyte tethering or rolling →	-0.153	-0.542	.001	.008	3	6
SOFT_TISSUE	Regulation of fibroblast proliferation →	+0.079	+1.192	.001	<.001	3	6
OVARY	Positive regulation of fibroblast proliferation →	+0.140	+0.915	<.001	<.001	3	6
LUNG_SCLC	Regulation of protein import into nucleus →	+0.078	+2.086	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,832 associations by consensus.

Positive regulation of intracellular transport by PINLYP expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →