Across TCGA patient cohorts, PINCR RNA expression is significantly associated with the mutation status of many other genes, with 8,451 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PINCR-associated genes across cancer lineages are TP53, PTEN, and FOXP1. Each is linked with PINCR in more than 5 cancer types. Because this analysis shows association rather than direction, both PINCR-to-partner and partner-to-PINCR results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PINCR→partner) and Y-score (partner→PINCR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	TP53 →	-2.218	-0.007	<.001	<.001	3	6
READ	PTEN →	+3.142	+0.085	.001	.002	3	4
BLCA	FOXP1 →	+3.930	+0.844	.004	<.001	3	4
PRAD	CADPS →	+3.865	+0.058	.006	<.001	3	3
PRAD	ARAP1 →	+4.865	+0.049	.002	<.001	3	3
HNSC	COL6A1 →	+4.193	+0.427	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,451 associations by consensus.

Exploration

PINCR survival (RNA) · tumor vs normal (RNA) · all PINCR data types