PIK3C2G

Across TCGA cell cohorts, PIK3C2G RNA expression is significantly associated with the go_rna of many other GO terms, with 472 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible PIK3C2G-associated GO terms across cancer lineages are Response to indole-3-methanol, Positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway, and Positive regulation of excitatory synapse assembly. Each is linked with PIK3C2G in more than 6 cancer types. Because this analysis shows association rather than direction, both PIK3C2G-to-partner and partner-to-PIK3C2G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to indole-3-methanol grouped by PIK3C2G-low versus PIK3C2G-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIK3C2G→partner) and Y-score (partner→PIK3C2G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Response to indole-3-methanol →	+0.171	+0.583	<.001	.006	3	7
UPPER_AERODIGESTIVE_TRACT	Positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway →	-0.223	-0.479	<.001	.001	3	4
UPPER_AERODIGESTIVE_TRACT	Positive regulation of excitatory synapse assembly →	+0.722	+0.503	.002	<.001	3	4
LUNG_NSCLC_LUAD	Lipoxygenase pathway →	-0.188	-0.286	<.001	.008	3	4
URINARY_TRACT	Cellular response to indole-3-methanol →	+0.141	+0.584	<.001	.005	1	6
BREAST	Protein localization to nucleoplasm →	-0.068	-0.713	.006	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 472 associations by consensus.

Response to indole-3-methanol by PIK3C2G expression — URINARY_TRACT

Explore this box plot interactively →