PIK3C2G

Across TCGA cell cohorts, PIK3C2G mutation is significantly associated with the mutation status of many other genes, with 5,615 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PIK3C2G-associated genes across cancer lineages are TEX14, NOTCH1, and ACACB. Each is linked with PIK3C2G in more than 5 cancer types. Because this analysis shows association rather than direction, both PIK3C2G-to-partner and partner-to-PIK3C2G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX14 grouped by PIK3C2G-low versus PIK3C2G-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIK3C2G→partner) and Y-score (partner→PIK3C2G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TEX14 →	+4.601	+3.169	.003	.003	1	6
CNS	NOTCH1 →	+2.862	+3.633	.008	.008	1	6
BREAST	ACACB →	+4.442	+5.095	.001	.001	1	5
SOFT_TISSUE	PTPRS →	+5.651	+5.651	<.001	<.001	1	5
LARGE_INTESTINE	DOCK3 →	+1.803	+2.828	<.001	<.001	1	5
STOMACH	BOD1L1 →	+3.440	+3.115	.003	.003	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,615 associations by consensus.

TEX14 by PIK3C2G expression — BLOOD_Lymphoma

Explore this box plot interactively →