PIH1D1

Across TCGA patient cohorts, PIH1D1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,758 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PIH1D1-associated genes across cancer lineages are RPAP3, KIF14, and SEH1L. Each is linked with PIH1D1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PIH1D1-to-partner and partner-to-PIH1D1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIH1D1 versus RPAP3 in LSCC, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIH1D1→partner) and Y-score (partner→PIH1D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RPAP3 →	+0.552	+0.192	<.001	<.001	3	8
LUAD	KIF14 →	+0.903	+0.144	<.001	<.001	3	5
LSCC	SEH1L →	+0.753	+0.228	<.001	<.001	3	5
OV	TMEM204 →	-0.757	-0.197	.003	.006	3	5
UCEC	TARBP2 →	+0.692	+0.156	.003	.002	2	6
OV	DENR →	+0.462	+0.349	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,758 associations by consensus.

PIH1D1 vs RPAP3 — LSCC

Explore this scatter interactively →