PIH1D1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PIH1D1 mutation is significantly associated with the RNA expression of many other genes, with 2,153 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PIH1D1-associated genes across cancer lineages are LINC01875, NDUFB9P1, and MIR8485. Each is linked with PIH1D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PIH1D1-to-partner and partner-to-PIH1D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01875 grouped by PIH1D1-low versus PIH1D1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIH1D1→partner) and Y-score (partner→PIH1D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCALINC01875 →+0.057+5.229<.001.00232
SKCMNDUFB9P1 →+0.113+4.215.004.00932
BRCAMIR8485 →+0.169+8.057<.001.00532
COADRPL7AP52 →+0.248+4.107<.001.00532
COADH3P2 →+0.689+3.951<.001.00532
COADHIKESHIP3 →+0.431+4.221<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,153 associations by consensus.

LINC01875 by PIH1D1 expression — BLCA

Box plot of LINC01875 in PIH1D1-low vs PIH1D1-high samples in BLCA.

Explore this box plot interactively →

Exploration