PIGU

Across TCGA patient cohorts, PIGU protein abundance is significantly associated with the protein abundance of many other proteins, with 23,960 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIGU-associated proteins across cancer lineages are PIGT, SMPD4, and TMCO1. Each is linked with PIGU in more than 9 cancer types. Because this analysis shows association rather than direction, both PIGU-to-partner and partner-to-PIGU results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIGU versus PIGT in UCEC, with a Pearson correlation of 0.77.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGU→partner) and Y-score (partner→PIGU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PIGT →	+0.549	+0.707	<.001	<.001	3	10
UCEC	SMPD4 →	+0.463	+0.565	<.001	<.001	3	9
CCRCC	TMCO1 →	+0.646	+0.404	<.001	<.001	3	9
BRCA	TMEM230 →	+0.675	+0.594	<.001	<.001	3	9
OV	AAR2 →	+0.316	+0.484	<.001	<.001	3	9
UCEC	DDOST →	+0.630	+0.722	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,960 associations by consensus.

PIGU vs PIGT — UCEC

Explore this scatter interactively →