PIGU

Across TCGA cell cohorts, PIGU mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PIGU-associated genes across cancer lineages are OR5V1 and MARCOL. Each is linked with PIGU in more than 1 cancer types. Because this analysis shows association rather than direction, both PIGU-to-partner and partner-to-PIGU results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5V1 grouped by PIGU-low versus PIGU-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGU→partner) and Y-score (partner→PIGU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR5V1 →	+0.008	+4.437	<.001	.004	3	1
LARGE_INTESTINE	MARCOL →	+1.186	+3.920	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR5V1 by PIGU expression — LARGE_INTESTINE

Explore this box plot interactively →