PIGS

Across TCGA patient cohorts, PIGS RNA expression is significantly associated with the RNA expression of many other genes, with 18,817 significant associations in total. ACC shows the largest number of these associations.

The most reproducible PIGS-associated genes across cancer lineages are CASC3, SUPT6H, and BECN1. Each is linked with PIGS in more than 33 cancer types. Because this analysis shows association rather than direction, both PIGS-to-partner and partner-to-PIGS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIGS versus CASC3 in ACC, with a Pearson correlation of 0.85.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGS→partner) and Y-score (partner→PIGS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	CASC3 →	+1.101	+1.364	<.001	<.001	3	34
ACC	SUPT6H →	+1.061	+1.490	<.001	<.001	3	34
ACC	BECN1 →	+1.300	+1.425	<.001	<.001	3	34
ACC	ACLY →	+1.728	+1.429	<.001	<.001	3	34
ACC	DCAF7 →	+1.057	+1.291	<.001	<.001	3	34
UCS	ADNP2 →	+1.362	+0.955	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,817 associations by consensus.

PIGS vs CASC3 — ACC

Explore this scatter interactively →