PIGL

Across TCGA patient cohorts, PIGL RNA expression is significantly associated with the protein abundance of many other proteins, with 12,119 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIGL-associated proteins across cancer lineages are METTL16, NCOR1, and TTC19. Each is linked with PIGL in more than 5 cancer types. Because this analysis shows association rather than direction, both PIGL-to-partner and partner-to-PIGL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIGL versus METTL16 in LSCC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGL→partner) and Y-score (partner→PIGL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	METTL16 →	+0.271	+0.528	<.001	<.001	3	6
BRCA	NCOR1 →	+0.313	+0.715	<.001	<.001	3	5
HNSC	TTC19 →	+0.358	+0.571	<.001	<.001	3	4
BRCA	NCOR1_S1322 →	+0.450	+0.566	.004	<.001	3	4
BRCA	NCOR1_S224 →	+0.473	+0.656	<.001	<.001	3	4
PDAC	SMARCC2_S347 →	+0.897	+0.253	.004	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,119 associations by consensus.

PIGL vs METTL16 — LSCC

Explore this scatter interactively →