PIGL

Across TCGA patient cohorts, PIGL protein abundance is significantly associated with the RNA expression of many other genes, with 4,007 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PIGL-associated genes across cancer lineages are MXD1, TUT7, and CYTH4. Each is linked with PIGL in more than 1 cancer types. Because this analysis shows association rather than direction, both PIGL-to-partner and partner-to-PIGL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIGL versus MXD1 in OV, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGL→partner) and Y-score (partner→PIGL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MXD1 →	+1.205	+0.845	<.001	<.001	3	2
OV	TUT7 →	+1.182	+0.781	.001	.003	3	2
OV	CYTH4 →	+1.716	+1.011	<.001	.002	3	1
OV	APOBEC3H →	+0.801	+0.830	.005	.001	3	1
OV	NCF4 →	+1.662	+0.933	<.001	.004	3	1
OV	DDHD1 →	+1.203	+0.863	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,007 associations by consensus.

PIGL vs MXD1 — OV

Explore this scatter interactively →