PIGL

Across TCGA patient cohorts, PIGL mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PIGL-associated genes across cancer lineages are Osteoblast, Endothelial cells, and Th2 cells. Each is linked with PIGL in more than 1 cancer types. Because this analysis shows association rather than direction, both PIGL-to-partner and partner-to-PIGL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Osteoblast grouped by PIGL-low versus PIGL-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGL→partner) and Y-score (partner→PIGL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Osteoblast →	+0.044	+3.669	<.001	.049	3	1
UCEC	Endothelial cells →	-0.046	-3.127	.026	.020	1	1
UCEC	Th2 cells →	+0.249	+3.169	.011	.020	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Osteoblast by PIGL expression — STAD

Explore this box plot interactively →