PIGG

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PIGG RNA expression is significantly associated with the protein abundance of many other proteins, with 9,397 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PIGG-associated proteins across cancer lineages are BOD1L1, WDR1, and GAK. Each is linked with PIGG in more than 5 cancer types. Because this analysis shows association rather than direction, both PIGG-to-partner and partner-to-PIGG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIGG versus BOD1L1 in BRCA, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGG→partner) and Y-score (partner→PIGG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCABOD1L1 →+0.259+0.404.002.00336
OVWDR1 →+0.493+0.916<.001<.00135
BRCAGAK →+0.228+0.552<.001<.00134
LUADSDF2L1 →-0.403-0.399<.001<.00134
PDACFKBP11 →-0.545-0.238<.001.00134
OVRASSF8_S105 →+0.799+0.718.007.00633
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,397 associations by consensus.

PIGG vs BOD1L1 — BRCA

Per-sample scatter of PIGG vs BOD1L1 in BRCA (Pearson r = 0.32).

Explore this scatter interactively →

Exploration