PIGG

Across TCGA cell cohorts, PIGG RNA expression is significantly associated with the go_rna of many other GO terms, with 4,179 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PIGG-associated GO terms across cancer lineages are Vacuole organization, Cilium or flagellum-dependent cell motility, and Transcription pausing by RNA polymerase II. Each is linked with PIGG in more than 15 cancer types. Because this analysis shows association rather than direction, both PIGG-to-partner and partner-to-PIGG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuole organization grouped by PIGG-low versus PIGG-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGG→partner) and Y-score (partner→PIGG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Vacuole organization →	+0.077	+0.829	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.085	-0.755	<.001	<.001	3	15
BONE	Transcription pausing by RNA polymerase II →	+0.139	+0.631	.003	.003	2	16
STOMACH	Macroautophagy →	+0.092	+0.891	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.085	-0.755	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Phospholipid biosynthetic process →	+0.045	+1.011	.001	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,179 associations by consensus.

Vacuole organization by PIGG expression — STOMACH

Explore this box plot interactively →