PIGFP2

Across TCGA patient cohorts, PIGFP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,303 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PIGFP2-associated GO terms across cancer lineages are Cellular response to carbohydrate stimulus, Regulation of protein ubiquitination, and Intracellular glucose homeostasis. Each is linked with PIGFP2 in more than 11 cancer types. Because this analysis shows association rather than direction, both PIGFP2-to-partner and partner-to-PIGFP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to carbohydrate stimulus grouped by PIGFP2-low versus PIGFP2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGFP2→partner) and Y-score (partner→PIGFP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Cellular response to carbohydrate stimulus →	+0.049	+0.245	<.001	<.001	3	12
STAD	Regulation of protein ubiquitination →	+0.060	+0.171	<.001	<.001	3	12
ESCA	Intracellular glucose homeostasis →	+0.052	+0.256	<.001	<.001	3	11
ESCA	Positive regulation of protein modification by small protein conjugation or removal →	+0.071	+0.271	<.001	<.001	3	11
STAD	Positive regulation of protein ubiquitination →	+0.057	+0.184	<.001	<.001	3	11
STAD	Regulation of protein serine/threonine kinase activity →	+0.047	+0.146	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,303 associations by consensus.

Cellular response to carbohydrate stimulus by PIGFP2 expression — ESCA

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