PIGFP2

Across TCGA pan-cancer cohorts, PIGFP2 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated PIGFP2 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher PIGFP2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PIGFP2 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

LUSC, SKCM, and ESCA are the cancer types where PIGFP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Tertile	III,IV	0.102	0.664	<.001	81	view →
SKCM	OS	Tertile	IV	0.179	0.755	<.001	54	view →
ESCA	OS	Quartile	All	0.557	0.744	.012	36	view →
READ	OS	Tertile	IV	0.111	0.893	<.001	27	view →
BLCA	DFS	Tertile	IV	0.128	0.477	<.001	18	view →
CESC	DFS	Tertile	IV	0.053	0.529	<.001	18	view →
BRCA	DFS	Tertile	II,III,IV	0.887	0.946	.009	15	view →
TGCT	OS	Tertile	All	0.868	0.986	.013	12	view →
HNSC	OS	Tertile	All	0.615	0.358	.036	9	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

PIGFP2–LUSC (DFS)

Open the LUSC breakdown →