PIGFP2

Across TCGA pan-cancer cohorts, PIGFP2 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of PIGFP2’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where PIGFP2 RNA is repressed in tumor relative to normal tissue. In most cancer types PIGFP2 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

COAD are the cancer types where PIGFP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PIGFP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	−0.021	.035	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

PIGFP2–COAD

Open the COAD breakdown →