PIGB

Across TCGA patient cohorts, PIGB RNA expression is significantly associated with the protein abundance of many other proteins, with 11,007 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PIGB-associated proteins across cancer lineages are UBR1, USP8, and SNX1. Each is linked with PIGB in more than 6 cancer types. Because this analysis shows association rather than direction, both PIGB-to-partner and partner-to-PIGB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIGB versus UBR1 in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGB→partner) and Y-score (partner→PIGB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	UBR1 →	+0.313	+0.593	<.001	<.001	3	7
OV	USP8 →	+0.253	+0.465	<.001	.001	3	5
BRCA	SNX1 →	+0.288	+0.522	<.001	<.001	3	5
OV	FBXO22 →	+0.395	+0.657	<.001	<.001	3	5
COAD	QRSL1 →	-0.268	-0.345	<.001	<.001	3	4
BRCA	REXO4 →	-0.473	-0.570	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,007 associations by consensus.

PIGB vs UBR1 — BRCA

Explore this scatter interactively →