PIBF1

Across TCGA patient cohorts, PIBF1 mutation is significantly associated with the RNA expression of many other genes, with 2,726 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PIBF1-associated genes across cancer lineages are RN7SKP108, RN7SL248P, and MIR4662B. Each is linked with PIBF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PIBF1-to-partner and partner-to-PIBF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP108 grouped by PIBF1-low versus PIBF1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIBF1→partner) and Y-score (partner→PIBF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SKP108 →	+0.056	+5.164	<.001	.002	3	3
THCA	RN7SL248P →	+0.104	+7.962	<.001	.007	3	2
UCEC	MIR4662B →	+0.118	+2.818	.006	.008	3	2
UCEC	MIR3189 →	+1.178	+2.958	<.001	.001	3	2
STAD	MIR4445 →	+0.998	+5.187	<.001	.007	3	2
BRCA	TOMM20P3 →	+0.225	+4.995	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,726 associations by consensus.

RN7SKP108 by PIBF1 expression — CESC

Explore this box plot interactively →