PI4KB

Across TCGA patient cohorts, PI4KB protein abundance is significantly associated with the RNA expression of many other genes, with 8,841 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PI4KB-associated genes across cancer lineages are PARP1, RABIF, and GORAB. Each is linked with PI4KB in more than 5 cancer types. Because this analysis shows association rather than direction, both PI4KB-to-partner and partner-to-PI4KB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PI4KB versus PARP1 in UCEC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PI4KB→partner) and Y-score (partner→PI4KB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PARP1 →	+0.759	+0.186	<.001	.001	3	6
LSCC	RABIF →	+0.463	+0.189	<.001	<.001	3	6
LSCC	GORAB →	+0.623	+0.209	<.001	<.001	3	5
UCEC	EPRS1 →	+0.862	+0.197	<.001	<.001	3	5
UCEC	GPATCH4 →	+0.738	+0.206	<.001	<.001	3	5
UCEC	SSR2 →	+0.733	+0.212	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,841 associations by consensus.

PI4KB vs PARP1 — UCEC

Explore this scatter interactively →