PHOX2B-AS1

Across TCGA patient cohorts, PHOX2B-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,695 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PHOX2B-AS1-associated GO terms across cancer lineages are Protein K63-linked ubiquitination, Membrane lipid metabolic process, and Ribose phosphate biosynthetic process. Each is linked with PHOX2B-AS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PHOX2B-AS1-to-partner and partner-to-PHOX2B-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein K63-linked ubiquitination grouped by PHOX2B-AS1-low versus PHOX2B-AS1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHOX2B-AS1→partner) and Y-score (partner→PHOX2B-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein K63-linked ubiquitination →	+0.076	+0.104	<.001	<.001	3	7
STAD	Membrane lipid metabolic process →	+0.050	+0.087	<.001	<.001	3	7
STAD	Ribose phosphate biosynthetic process →	+0.072	+0.083	<.001	<.001	3	7
STAD	Fibroblast proliferation →	+0.072	+0.100	<.001	<.001	3	7
STAD	Regulation of neural precursor cell proliferation →	+0.051	+0.071	<.001	<.001	3	7
STAD	Response to axon injury →	+0.056	+0.066	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,695 associations by consensus.

Protein K63-linked ubiquitination by PHOX2B-AS1 expression — STAD

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