PHF5GP

Across TCGA pan-cancer cohorts, PHF5GP RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated PHF5GP data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher PHF5GP RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PHF5GP expression acts as an unfavorable survival marker, although some lineages such as LUSC and STAD show a favorable association.

LUSC, STAD, and UVM are the cancer types where PHF5GP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Tertile	All	0.836	0.709	<.001	90	view →
STAD	OS	Quartile	II,III,IV	0.742	0.396	.002	69	view →
UVM	DFS	Tertile	All	0.492	0.820	<.001	66	view →
KIRC	DFS	Median	II,III,IV	0.874	0.740	.003	43	view →
DLBC	OS	Tertile	All	0.401	0.956	.001	33	view →
ESCA	OS	Median	IV	0.222	0.698	.006	30	view →
LIHC	DFS	Tertile	II,III,IV	0.189	0.433	<.001	27	view →
THYM	DFS	Tertile	III,IV	1.000	0.527	.033	15	view →
BLCA	OS	Quartile	II,III,IV	0.796	0.688	.031	12	view →
READ	DFS	Tertile	IV	0.301	0.688	.038	9	view →
KICH	DFS	Tertile	All	0.623	0.940	.028	7	view →
BRCA	OS	Tertile	III,IV	0.667	0.477	.026	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

PHF5GP–LUSC (DFS)

Open the LUSC breakdown →