PHF19

Across TCGA patient cohorts, PHF19 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,736 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PHF19-associated proteins across cancer lineages are RRM2, SMC4, and MCM2. Each is linked with PHF19 in more than 6 cancer types. Because this analysis shows association rather than direction, both PHF19-to-partner and partner-to-PHF19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHF19 versus RRM2 in CCRCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF19→partner) and Y-score (partner→PHF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RRM2 →	+0.589	+0.366	<.001	.008	3	7
GBM	SMC4 →	+0.740	+0.832	<.001	<.001	3	7
BRCA	MCM2 →	+0.672	+0.957	<.001	<.001	3	7
PDAC	MCM4 →	+0.628	+0.334	<.001	<.001	3	7
GBM	MCM6 →	+0.726	+0.660	<.001	.002	3	7
BRCA	MCM7 →	+0.657	+0.817	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,736 associations by consensus.

PHF19 vs RRM2 — CCRCC

Explore this scatter interactively →