PHC2-AS1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PHC2-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,059 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PHC2-AS1-associated proteins across cancer lineages are MBD3, MCM5, and MDC1. Each is linked with PHC2-AS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PHC2-AS1-to-partner and partner-to-PHC2-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHC2-AS1 versus MBD3 in LSCC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PHC2-AS1→partner) and Y-score (partner→PHC2-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCMBD3 →+0.564+0.892<.001<.00135
OVMCM5 →+0.557+0.826.003.00335
BRCAMDC1 →+0.520+0.655<.001<.00135
LSCCU2SURP →+0.263+0.749.002<.00134
HNSCUSP39 →+0.235+0.760.002.00334
GBMXAB2 →+0.186+0.696.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,059 associations by consensus.

PHC2-AS1 vs MBD3 — LSCC

Per-sample scatter of PHC2-AS1 vs MBD3 in LSCC (Pearson r = 0.54).

Explore this scatter interactively →

Exploration