PHACTR3-AS1

Across TCGA patient cohorts, PHACTR3-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,543 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PHACTR3-AS1-associated proteins across cancer lineages are SIPA1L1_S1528, INPP4A, and MAP1A_S1326. Each is linked with PHACTR3-AS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PHACTR3-AS1-to-partner and partner-to-PHACTR3-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHACTR3-AS1 versus SIPA1L1_S1528 in GBM, with a Pearson correlation of -0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PHACTR3-AS1→partner) and Y-score (partner→PHACTR3-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SIPA1L1_S1528 →	-0.507	-1.166	<.001	<.001	3	3
GBM	INPP4A →	+0.179	+1.173	<.001	<.001	3	3
PDAC	MAP1A_S1326 →	+0.652	+0.029	.001	.003	3	3
GBM	PPP1R14A →	+0.717	+1.081	<.001	<.001	3	3
GBM	ADD1_S59 →	+0.512	+0.936	<.001	<.001	3	3
GBM	RGS12_S694 →	+0.361	+1.368	.008	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,543 associations by consensus.

PHACTR3-AS1 vs SIPA1L1_S1528 — GBM

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